Thanks Michael.

Your theory is correct. However, if i use IA like AD621 that has pin-strapable gain of 100, then i reduce the chances of gain error due to Gain-resistor (resistor drift, tollerance, temperature-tracking, mismatch).

Also, if all the 4x channel circuits are within the same enclosure, theoretically all components are at the same temperature. Hence any temperature variance will affect the drift of all the components equally. Or will it be different ?

For all, here is how i am envisioning the amplifier.

Conventional amps are a single board entity with fixed 4x (or 6x in some cases) channels. My primary reason to design an amp, among other reasons, is to have a modular amp. Within this, each channel signal conditioner will be a plug-in module on a main summing board. See the attached image for the concept.

In the field, i have seen quite a few cases where 1 or 2 channels of the amp got "burned / shorted" due to various reasons, like moisture, lightning, etc. This called for a complete replacement of the amplifier AND then, re-calibration of all the load cells channels (10 or 20 turn trimpots).

In the modular concept, theoretically, if a single channel fails, only that particular channel module needs to be replaced. This reduces long-term costs and re-calibration time.

I know this is a debatable theory, might have its ups and downs, and i am wellcome to suggestions.

Regards,
Zeeshan