If one is willing to take the pains to construct a circuit meticulously, seeing to the limitations that the architecture of these boards imposes, and can convince himself that these limitations don't rule out their use in the first place, then they're probably useable.

However, if one is willing to put forth the effort to do that, it's easier, and better in my view, to do so with point-to-point-soldered wiring on a solid-ground-planed perf-board with plated-through holes to allow repeated soldering as needed. The work product one can produce on those will seldom be matched with what one can create on a "ProtoBoard."

RE